Orally Disintegrating Tablets: Why Moisture Control Makes or Breaks the Dose
Moisture Is the Variable That Decides Whether an ODT Works Orally disintegrating tablets, or ODTs, are built around a paradox: they must stay dry during storage and transport, then take on moisture instantly once they hit the tongue. The physical steps of proper ODT handling only look simple because the real engineering problem is hidden. A good ODT is not just a tablet that breaks apart quickly. It is a tablet that survives humidity long enough to reach the mouth intact. ...